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液滴測(cè)序(DROP-SEQ)
細(xì)胞是生物結(jié)構(gòu)和功能的基本單位,種類和狀態(tài)差異很大。
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單細(xì)胞懸液制備的方法講述
當(dāng)實(shí)體組織被分散成單細(xì)胞時(shí),分離方法可能會(huì)對(duì)細(xì)胞的性質(zhì)產(chǎn)生瞬時(shí)或持續(xù)的影響,而對(duì)單細(xì)胞懸液制備方法有哪些?
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RNA-Seq reveals the extent of small RNAs representation in t
While the amount of small non-coding RNA sequencing data is continuously increasing, it is still unclear to which extent small RNAs are represented in the human genome. Saarland University researchers have analyzed 303 billion sequencing rea
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Single cell sequencing sheds light on why cancers form in sp
While many cells in our bodies can accumulate oncogenic mutations, the majority of these events do not lead to tumor formation as these abnormal cells are eliminated by defense mechanisms. Instead, tumors arise when a mutation happens in a p
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Comparative analysis of single-cell RNA-sequencing methods
Single-cell mRNA sequencing (scRNA-seq) allows to profile heterogeneous cell populations, offering exciting possibilities to tackle a variety of biological and medical questions. A range of methods has been recently developed, making it nece
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Inertial-ordering-assisted droplet microfluidics for high-th
Single-cell RNA-seq reveals the cellular heterogeneity inherent in the population of cells, which is very important in many clinical and research applications. Recent advances in droplet microfluidics have achieved the automatic isolation, l
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Drop-seq- McCarroll Lab
Drop-seq is a technology we developed to enable biologists to analyze RNA expression genome-wide in thousands of individual cells at once. We first described this in a 2015 paper in Cell. Though commercial implementations of droplet-
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